Patients with IDH1 wild type anaplastic astrocytoms exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of glioamas.

Hartmann C, Hentschel B, Wick W, Capper D, Felsberg J, Simon M, Westphall M, Schackert G, Meyermann R, Pietsch T, Reifenberger G, Weller M, Loeffler M, von Deimling A.

Acta Neuropathol. 2010;120: 707-718